What are vectors in Infection Control

What are vectors in Infection Control

A mosquito shortly after obtaining blood from a human (note the droplet of blood plasma being expelled as the mosquito squeezes out excess water). Mosquitos are a vector for several diseases, including malaria.

In epidemiology, a disease vector is any living[1] agent that carries and transmits an infectious pathogen to another living organism;[2][3] agents regarded as vectors are organisms, such as parasites or microbes. The first major discovery of a disease vector came from Ronald Ross in 1897, who discovered the malaria pathogen when he dissected a mosquito.[4]

Arthropods[edit]

What are vectors in Infection Control

Arthropods form a major group of pathogen vectors with mosquitoes, flies, sand flies, lice, fleas, ticks, and mites transmitting a huge number of pathogens. Many such vectors are haematophagous, which feed on blood at some or all stages of their lives. When the insects feed on blood, the pathogen enters the blood stream of the host. This can happen in different ways.[5][6]

The Anopheles mosquito, a vector for malaria, filariasis, and various arthropod-borne-viruses (arboviruses), inserts its delicate mouthpart under the skin and feeds on its host's blood. The parasites the mosquito carries are usually located in its salivary glands (used by mosquitoes to anaesthetise the host). Therefore, the parasites are transmitted directly into the host's blood stream. Pool feeders such as the sand fly and black fly, vectors for pathogens causing leishmaniasis and onchocerciasis respectively, will chew a well in the host's skin, forming a small pool of blood from which they feed. Leishmania parasites then infect the host through the saliva of the sand fly. Onchocerca force their own way out of the insect's head into the pool of blood.[7][8]

Triatomine bugs are responsible for the transmission of a trypanosome, Trypanosoma cruzi, which causes Chagas Disease. The Triatomine bugs defecate during feeding and the excrement contains the parasites, which are accidentally smeared into the open wound by the host responding to pain and irritation from the bite.[9][10][11][12]

There are several species of Thrips that act as vectors for over 20 viruses, especially Tospoviruses, and cause all sorts of plant diseases.[13][14]

Plants and fungi[edit]

Some plants and fungi act as vectors for various pathogens. For example, the big-vein disease of lettuce was long thought to be caused by a member of the fungal division Chytridiomycota, namely Olpidium brassicae. Eventually, however, the disease was shown to be viral. Later it transpired that the virus was transmitted by the zoospores of the fungus and also survived in the resting spores. Since then, many other fungi in the Chytridiomycota have been shown to vector plant viruses.[15]

Many plant pests that seriously damage important crops depend on other plants, often weeds, to harbour or vector them; the distinction is not always clear. In the case of Puccinia graminis for example, Berberis and related genera act as alternate hosts in a cycle of infection of grain.[16]

More directly, when they twine from one plant to another, parasitic plants such as Cuscuta and Cassytha have been shown to convey phytoplasmal and viral diseases between plants.[17] [15]

Mammals[edit]

Rabies is transmitted through exposure to the saliva or brain tissue of an infected animal. Any warm-blooded animal can carry rabies, but the most common vectors are dogs, skunks, raccoons, and bats.[18]

World Health Organization and vector-borne disease[edit]

The World Health Organization (WHO) states that control and prevention of vector-borne diseases are emphasizing "Integrated Vector Management (IVM)",[19] which is an approach that looks at the links between health and environment, optimizing benefits to both.[a][20]

In April 2014, WHO launched a campaign called “Small bite, big threat” to educate people about vector-borne illnesses. WHO issued reports indicating that vector-borne illnesses affect poor people, especially people living in areas that do not have adequate levels of sanitation, drinking water and housing.[21]

Vector-borne zoonotic disease and human activity[edit]

What are vectors in Infection Control

Several articles, recent to early 2014, warn that human activities are spreading vector-borne zoonotic diseases.[b] Several articles were published in the medical journal The Lancet, and discuss how rapid changes in land use, trade globalization, and "social upheaval" are causing a resurgence in zoonotic disease across the world.[22]

Examples of vector-borne zoonotic diseases include:[23]

  • Lyme disease
  • Plague
  • West Nile virus

Many factors affect the incidence of vector-borne diseases. These factors include animals hosting the disease, vectors, and people.[23]

Humans can also be vectors for some diseases, such as Tobacco mosaic virus, physically transmitting the virus with their hands from plant to plant.

See also[edit]

  • Airborne disease
  • Asymptomatic carrier
  • Fomite
  • Globalization and disease
  • Insect vectors of human pathogens
  • Insect vectors of plant pathogens
  • VectorBase: genomic database of invertebrate vectors of human pathogens
  • List of diseases caused by insects
  • Natural reservoir
  • Waterborne disease
  • 2007 Yap Islands Zika virus outbreak

Notes[edit]

  1. ^ "IVM strategies are designed to achieve the greatest disease control benefit in the most cost-effective manner, while minimizing negative impacts on ecosystems (e.g. depletion of biodiversity) and adverse side-effects on public health from the excessive use of chemicals in vector control."[20]
  2. ^ "Vector-borne zoonotic diseases are those that naturally infect wildlife and are then transmitted to humans through carriers, or vectors, such as mosquitoes or ticks."[22]

References[edit]

  1. ^ "Vector-borne diseases".
  2. ^ "Vector". WordNet Search 3.1. Princeton University. Retrieved 7 April 2014.
  3. ^ Last, James, ed. (2001). A Dictionary of Epidemiology. New York: Oxford University Press. p. 185. ISBN 978-0-19-514169-6. OCLC 207797812.
  4. ^ Prevention, CDC-Centers for Disease Control and (2017-03-28). "CDC - Malaria - About Malaria - History - Ross and the Discovery that Mosquitoes Transmit Malaria Parasites". www.cdc.gov. Retrieved 2020-10-23.
  5. ^ "Classification of Animal Parasites". plpnemweb.ucdavis.edu.
  6. ^ Garcia, Lynne S. (August 15, 1999). "Classification of Human Parasites, Vectors, and Similar Organisms". Clinical Infectious Diseases. 29 (4): 734–736. doi:10.1086/520425. PMID 10589879.
  7. ^ "8.20D: Arthropods as Vectors". 23 June 2017.
  8. ^ "PEOI Foundations of Public Health".
  9. ^ "CDC - Chagas Disease - Detailed Fact Sheet". 11 April 2022.
  10. ^ "Coronavirus disease 2019 (COVID-19) from Mayo Clinic - Mayo Clinic". Mayo Clinic.
  11. ^ "CDC - Chagas Disease - General Information". 13 April 2022.
  12. ^ "Chagas disease".
  13. ^ "Thripidae - an overview | ScienceDirect Topics".
  14. ^ "Thysanoptera - an overview | ScienceDirect Topics".
  15. ^ a b R. S. Mehrotra (2013). Fundamentals of Plant Pathology. Tata McGraw-Hill Education. pp. 342–. ISBN 978-1-259-02955-4.
  16. ^ Peter W. Price (1980). Evolutionary Biology of Parasites. Princeton University Press. pp. 61–. ISBN 0-691-08257-X.
  17. ^ Haynes, A R. et al. Comparison of two parasitic vines: Dodder (Cuscuta) and Woe vine(Cassytha). Florida Dept Agric & Consumer Services. Division of Plant Industry. Botany Circular No. 30. January/February 1996
  18. ^ "Raccoons and public health". The Humane Society of the United States. Retrieved 2022-04-01.
  19. ^ "Handbook for Integrated Vector Management" (PDF). World Health Organization. Retrieved 3 December 2015.
  20. ^ a b "Vector-borne disease". The Health and Environment Linkages Initiative (HELI). Geneva, Switzerland: World Health Organization. Retrieved 7 April 2014.
  21. ^ Parrish, Ryan (7 April 2014). "WHO focuses on vector-borne diseases for World Health Day 2014". Vaccine News Daily. Chicago, Illinois. Retrieved 7 April 2014.
  22. ^ a b Purlain, Ted (5 December 2012). "Lancet addresses emerging infectious vector-borne diseases". Vaccine News Daily. Chicago, Illinois. Retrieved 7 April 2014.
  23. ^ a b University of California - Santa Cruz (30 November 2012). "Emerging vector-borne diseases create new public health challenges". Science Daily. Rockville, Maryland. Retrieved 7 April 2014.

Bibliography[edit]

  • "Better environmental management for control of dengue". The Health and Environment Linkages Initiative (HELI). Geneva, Switzerland: World Health Organization. Retrieved 7 April 2014.
  • "Division of Vector-Borne Diseases (DVBD)" (Multimedia). Fort Collins, Colorado: Centers for Disease Control and Prevention (CDC). Retrieved 7 April 2014.
  • "Issue Brief Series: Vector-borne Diseases" (PDF). Healthy Environments for Children Alliance. Geneva, Switzerland: World Health Organization. Retrieved 7 April 2014.
  • "Malaria control: the power of integrated action". The Health and Environment Linkages Initiative (HELI). Geneva, Switzerland: World Health Organization. Retrieved 7 April 2014.
  • Pawan, J.L. (1936). "Transmission of the Paralytic Rabies in Trinidad of the Vampire Bat: Desmodus rotundus murinus Wagner, 1840." Annual Tropical Medicine and Parasitol[clarification needed], 30, April 8, 1936:137–156.
  • Pawan, J.L. "Rabies in the Vampire Bat of Trinidad with Special Reference to the Clinical Course and the Latency of Infection." Annals of Tropical Medicine and Parasitology. Vol. 30, No. 4. December 1936
  • Quammen, David (4 April 2013). "Planet of the Ape; 'Between Man and Beast,' by Monte Reel". The New York Times. Retrieved 7 April 2014.
  • "Vector-borne diseases". Articles about vector-borne disease. Vaccine News Daily. Chicago.
  • WHO page on vector-borne diseases
  • Biological mosquito eradication in Monte Verde, Honduras
  • The National Center for Biotechnology Information, Vector-borne Diseases: Understanding the Environmental, Human Health, and Ecological Connections
  • Science Direct, Current Research in Parasitology and Vector-borne Diseases
  • Science Direct, Vector-borne Diseases
  • CDC Diseases Carried by Vectors

What are the 4 major disease vectors?

Disease vectors.
Malaria (protozoan): Anopheles species of mosquito..
Lymphatic filariasis (nematode worm): Culex, Anopheles, Aedes species of mosquito..
Dengue (virus): Aedes species of mosquito..
Leishmaniasis (protozoan): mainly Phlebotomus species of sandfly..

What are 3 common vectors of infectious diseases?

Vector-borne diseases are infections transmitted by the bite of infected arthropod species, such as mosquitoes, ticks, triatomine bugs, sandflies, and blackflies.

What are vectors explain with an example?

A vector is a quantity or phenomenon that has two independent properties: magnitude and direction. The term also denotes the mathematical or geometrical representation of such a quantity. Examples of vectors in nature are velocity, momentum, force, electromagnetic fields, and weight.

What's the difference between vector and pathogen?

In simple words, a pathogen is defined as the cause of a disease, while a vector is a carrier of a pathogen.